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tecovirimat will increase the level or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep an eye on. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse effects if coadministered with delicate substrates of such enzymes.butabarbital will reduce the extent or result of diazepam by influen